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Department of Evolutionary Anthropology

Ana Maria Agapito

Research Interests

Finding out how evolution can be evidenced through genetic processes has always been my research interest, using population genetics is how I learned to approach this. Even better, learning how to  use this knowledge as an evidence for conservation. Population genomics is the main research topic, the main phenomena I have researched are hybridization and admixture. For my PhD thesis I want to take the next step and
(1) assess evolution in another time dimension, using extinct population's genetic data;
(2) associate statistically adaptations to environmental variables.

Academic Record

2019 Master in Biological Sciences. Mention in Evolutionary Biology. Bio-Bio University, Chillan, Chile. Faculty of Science.

2015 Bachelor in Biology. Universidad Peruana Cayetano Heredia (UPCH), Lima – Peru. Faculty of Sciences and Philosophy 'Alberto Cazorla Talleri'

Research Bio

This project will look at both of population genomic aspects (adaptive evolution and demographic history) of orang-utans using extant and extinct genetic data. Orang-utans (Pongo sp.) are currently distributed in the islands of Borneo and Sumatra but were initially distributed across Sundaland, reaching parts of Java and Southern China. With the use of ancient DNA techniques, museum samples allow us to delve deeper into the past genetic history of orang-utans, including extinct populations. Genome segments obtained from these historic samples would allow us to screen genetic diversity from new populations and compare them to the current populations which we have sampled.

The first part of this thesis will explore changes in Bornean and Sumatran orang-utans’ genetic diversity levels using historic DNA samples to see if there has been a loss of genetic diversity within their populations of the last two centuries compared to populations from the present. We will also infer historic species ranges using museum samples to see if Pongo tapanuliensis had the same restricted geographic range.

Geographical changes and climatic oscillations are thought to have acted as selective forces that produced the adaptations we see today at a genomic level in orang-utans. Previous work showed significant differences in the adaptive evolution of P. pygmaeus and P. abelii, which can be explained by long-lasting environmental differences. However, the adaptive evolution of orang-utans has not yet been explored in a more fine-grained manner, especially at smaller geographic scales in Borneo, where orang-utans occur in diverse habitats.

The second part of the PhD project will deepen the study of orang-utan adaptations by associating them to environmental variables in a population-wise manner. We will detect drivers of these adaptations using a landscape genomics approach, integrating the genomic results with abiotic and biotic information from the past and present.

Previous Research

M2 internship: Crop-wild introgression and demographic insight in apples (Malus genus).

Master thesis: Solving demographic dynamics of South American camelids: domestication and hybridization.

Bachellor thesis: Keratin associated protein gene’s (KRTAPs) phylogeny of South American camelids.


  • Marín, J. C., Rivera, R., Varas, V., Cortés, J., Agapito, A., Chero, A., Chavez, A., Johnson, W. E. & Orozco-terWengel, P. (2018). Genetic variation in coat colour genes MC1R and ASIP provides insights into domestication and management of South American camelids. Frontiers in Genetics, 9, 487.
  • B. A. González, J. P. Vásquez, D. Gómez-Uchida, J. Cortés, R. Rivera, N. Aravena, A. M. Chero, A. M. Agapito, V. Varas, J. C. Wheeler, P. Orozco-terWengel, & J. C. Marín. (2019) Phylogeography and population genetics of Vicugna vicugna: evolution in the arid Andean high plateau. Frontiers in Genetics 10, 445.
  • González, B. A., Agapito, A. M., Novoa-Muñoz, F., Vianna, J., Johnson, W. E., & Marín, J. C. (2020). Utility of genetic variation in coat color genes to distinguish wild, domestic and hybrid South American camelids for forensic and judicial applications. Forensic Science International: Genetics, 45, 102226.

Weiterführende Informationen

Ana Maria Agapito

Ana Maria Agapito